Carbapenems

Carbapenems are powerful broad-spectrum antibiotics that are often the last line of effective treatment for patients with multidrug-resistant infections, including those caused by ESBL-producing bacteria (extended spectrum beta-lactamases).

Cases of carbapenem resistance in E. coli and Klebsiella in the UK started to increase during 2008 and 2009.

Antimicrobial resistance (AMR) is resistance of a micro-organism to an antimicrobial medicine to which it was previously sensitive. Resistant organisms (they include bacteria and viruses) are able to withstand attack by antimicrobial medicines, such as antibiotics and antivirals, so that standard treatments become ineffective and infections are prolonged, with longer periods of infectivity, and may spread to others. Inappropriate and irrational use of antimicrobial medicines provides favourable conditions for resistant micro-organisms to emerge, spread and persist.

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Disclaimer: the main purpose of this blog is to assemble my notes for my Continuing Professional Development (CPD). The topic discussed here should not be referred to as the only source of information use it in combination. It should be used with other established reference sources. If you are using it significantly after the date of initial publication, then you should refer to current published evidence. 

.If the content of this article concerns you, please contact your doctor or pharmacist

 مطالب مندرج در این وبلاگ صرفا برای اطلاع رسانی و افزایش آگاهی در رابطه با سلامت و بهداشت می باشد و الزاما مرجع کاملی در رابطه با موضوع مورد بحث نمی باشد. برای اطلاعات بیشتر جهت درمان، قطع یا تغییر نوع درمان با پزشک معالج یا داروساز خود مشورت نمایید

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